Product Overview
Our 500L Vacuum Pharmaceutical Mixer for Toothpaste stands as a cornerstone in dental care production, offering GMP precision for high-quality toothpaste formulations. Its advanced vacuum system achieves an impressive -0.09 MPa pressure, effectively eliminating air bubbles that can compromise texture and shelf life. This level of vacuum ensures sterile homogeneity even for complex formulations containing fluoride, abrasives, and natural extracts. Crafted from 316L stainless steel with a mirror-polished surface (Ra≤0.4μm), the mixer resists corrosion from acidic ingredients like citric acid and maintains pharmaceutical-grade hygiene. The PLC-controlled variable speed mixing system (0–60 RPM for mixer, 0-2960RPM for homogenizer, 0-1440RPM for dispenser) seamlessly adapts to viscous products, making it suitable for everything from lightweight gel toothpastes to heavy-duty abrasive formulas.
Product Specifications
Features
1. Vacuum-Driven Homogeneity
The mixer’s double-stage vacuum pump removes entrapped air down to <0.1% air content, eliminating voids that cause inconsistent texture or ingredient separation. This is particularly critical for fluoride particles (e.g., sodium monofluorophosphate) and abrasives like silica, preventing gritty textures and ensuring each use delivers consistent cleaning power. The vacuum also reduces oxidation, preserving the effectiveness of sensitive ingredients such as xylitol and probiotics.
2. Hygienic Design
Equipped with a triple-seal hermetic system (PTFE gaskets + mechanical seals + vacuum monitoring), the mixer minimizes cross-contamination risks between batches. Its automated CIP (Clean-in-Place) system performs a 3-stage cleaning cycle (pre-rinse, detergent wash, sanitizing rinse) without disassembly, reducing cleaning time by 60% compared to manual methods. The sloped bottom design and PTFE-coated scraper blades ensure complete material discharge, lowering waste to <0.5%—a critical factor for cost control in high-volume production.
3. Process Optimization
PLC continuously monitor key parameters: temperature, vacuum level, mixing torque, and viscosity. Data is displayed in real time on a touchscreen. The mixer’s recipe memory function stores formulas, allowing check between mint, whitening, sensitive, and natural toothpaste variants.
Applications
Toothpaste Production: Handles abrasive gels, fluoride suspensions, herbal extracts, and children’s formulations with safe, non-abrasive textures.
Pharmaceuticals: Processes medicated ointments, topical analgesics, and oral care medications requiring sterile mixing conditions.
Cosmetics: Blends high-viscosity products such as lip balms, petroleum jelly-based creams, and facial masks.
Food Industry: Mixes peanut butter, chocolate spreads, and high-fat emulsions with uniform consistency and reduced air content.
FAQ
Q: How does the vacuum system improve toothpaste quality?
A: By reducing air, it prevents oxidation of active ingredients like sodium fluoride (which degrades in oxygen-rich environments) and eliminates bubbles that cause tube expansion or product drying. This extends shelf life compared to non-vacuum mixing.
Q: What is the typical mixing cycle time?
A: For standard toothpaste formulations, cycles range from 20–40 minutes. High-viscosity gel-based toothpastes or those containing multiple phases (e.g., striped designs) may require 60–90 minutes to achieve complete homogeneity.
